Hormone Levels Throughout the Menstrual Cycle


The following tables show the amount of hormones present in the blood of "healthy fertile women with normal sexual function" during the three phases of their menstrual cycle. The values presented are from The Journal of Sexual Medicine Volume 2 Supplement 1 Jan. 2005 Pg 13.

The follicular phase is days one, the first day of menstruation, through day fourteen, the ovulatory phase is the period of ovulation (around day fourteen), and the luteal phase is days fifteen through twenty-eight in a twenty-eight day cycle. A clear graphical representation of the hormonal changes during the menstrual cycle can be seen on the following webpage:

http://sprojects.mmi.mcgill.ca/menstrualcycle/physiology.html

Illustration by Patsy

It is important to note the broad range of the measured levels, as some women in the study had a "normal" level of a specific hormone that was ten times greater than the mean or average value. An average can be very misleading when evaluating a unique individual.

Follicular Phase

Hormone

Mean (Average) Value Range Units
E2 (Estradiol) 83.34 10.9-406.2 pg/ml
Progesterone 0.89 0.19-9.25 ng/ml
Total Testosterone 0.40 0.11-0.73 ng/ml
Free Testosterone 1.33 0.14-3.5 pg/ml
SHBG 74.57 13.2-206.0 nmol/L
delta4-androstenedione 1.75 0.38-3.98 ng/ml
DHEAS 1,985.68 468-5,800 ng/ml
Prolactin 10.20 3.04-32.51 ng/ml

Ovulatory Phase

Hormone

Mean (Average) Value Range Units
E2 (Estradiol) 156.42 13.2-584.9 pg/ml
Progesterone 3.12 0.15-18.90 ng/ml
Total Testosterone 0.50 0.15-1.04 ng/ml
Free Testosterone 1.49 0.20-3.8 pg/ml
SHBG 80.98 16.0-279.0 nmol/L
delta4-androstenedione 1.97 0.30-6.31 ng/ml
DHEAS 2,040.75 180-5,820 ng/ml
Prolactin 11.14 2.79-34.82 ng/ml

Luteal Phase

Hormone

Mean (Average) Value Range Units
E2 (Estradiol) 156.26 51.0-527.1 pg/ml
Progesterone 10.26 0.18-32.50 ng/ml
Total Testosterone 0.46 0.13-0.94 ng/ml
Free Testosterone 1.36 0.24-3.4 pg/ml
SHBG 81.81 16.0-257.0 nmol/L
delta4-androstenedione 1.88 0.32-3.90 ng/ml
DHEAS 2,036.35 183-6,080 ng/ml
Prolactin 10.85 2.88-33.04 ng/ml

Change In Average Hormone Levels Throughout Menstrual Cycle - Mean Values

Hormone

Follicular Phase Ovulatory Phase Luteal Phase Units
E2 (Estradiol) 83.34 156.42 156.26 pg/ml
Progesterone 0.89 3.12 10.26 ng/ml
Total Testosterone 0.40 0.50 0.46 ng/ml
Free Testosterone 1.33 1.49 1.36 pg/ml
SHBG 74.57 80.98 81.81 nmol/L
Delta4-androstenedione 1.75 1.97 1.88 ng/ml
DHEAS 1,985.68 2,040.75 2,036.35 ng/ml
Prolactin 10.20 11.14 10.85 ng/ml

Change In Average Hormone Levels Throughout Menstrual Cycle
Based on Mean Values

Expressed in Same Unit of Measure

Hormone

Follicular Phase Ovulatory Phase Luteal Phase Units
E2 (Estradiol) 83.34 156.42 156.26 pg/ml
Progesterone 890 3,120 10,260 pg/ml
Total Testosterone 400 500 460 pg/ml
Free Testosterone 1.33 1.49 1.36 pg/ml
SHBG *        
Delta4-androstenedione 1,750 1,970 1,880 pg/ml
DHEAS 1,985,680 2,040,750 2,036,350 pg/ml
Prolactin 10,200 11,140 10,850 pg/ml

* Original data expressed in units not convertible to other units of measure


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